ISDIN
vs PCA SKIN
Two formulas, with different prices and ingredient blends.
| What to compare | ISDIN Hyaluronic Concentrate | PCA SKIN Hyaluronic Acid Boosting Serum |
|---|---|---|
| US reference price | $115 / 30 mL · $3.83/mL | $128 / 30 mL · $4.27/mL |
| HA forms | Low- and medium-molecular-weight HA, according to brand | Hyaluronic acid, hydrolyzed HA, sodium hyaluronate |
| Disclosed concentrations | Not disclosed | HA and niacinamide percentages not disclosed |
| Other ingredients to consider | BioMarine extract, peptides, lentil extract | Glycerin, dimethicone, niacinamide, ceramides NP/AP/EOP |
| Format | Water-gel; pump; satin finish | Serum; pump |
| Evidence status | Brand user-perception claims plus ingredient-level HA evidence. | Six-week serum study with 40 women; no vehicle-control group described in abstract. |
The practical difference
ISDIN: The water-gel format and pump may appeal if you want a lightweight step under moisturiser.
PCA SKIN: A broader hydration formula that includes niacinamide and barrier lipids alongside HA.
What the comparison cannot tell you
ISDIN: The brand’s reported user-perception results are data on file, not a published head-to-head trial. Molecular weights in kDa are not supplied on the checked page.
PCA SKIN: The page’s 50% HA increase is based on laboratory data. Its ingredient list also includes aroma and rosemary oil. The niacinamide percentage cannot be assumed to match a 5% trial.
These published details do not establish a clinical winner. No head-to-head study of this pair was identified in this review. Prices were checked 2 November 2026; confirm current local prices.
Read the ingredient evidence