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Uncontrolled clinical study · 2006

Alternating blue and red light for acne

A small study that also used skin exfoliation. Spots improved, but the study cannot separate the effects of light and exfoliation.

The main finding. Spots improved, but the study cannot separate the effects of light and exfoliation.

By Nota Cutis, editorial team · Reviewed

Goldberg DJ, Russell BA. J Cosmet Laser Ther. 2006;8(2):71–5. PubMed 16766484 · DOI

How the study worked

Twenty-four people had eight treatments, twice a week. Sessions alternated 415 nm blue and 633 nm red light and lasted 20 minutes. Each was preceded by mild microdermabrasion, a form of exfoliation.

Researchers counted spots at the start and at weeks 2, 4, 8 and 12.

The results

Twenty-two people completed the study. Spot counts fell by 46% at four weeks and 81% at twelve weeks. Inflamed spots improved more than blackheads and whiteheads. Severe acne improved slightly more than mild acne. Side effects were mild and brief.

What is still unclear

There was no comparison group. Exfoliation before every session may have contributed to the result.

What to take from this

Spots improved, but the study cannot separate the effects of light and exfoliation.

Devices that list similar light

Three of the 5 masks in the comparison list a wavelength in every band used here (blue near 415 nm and red near 633 nm). They are examples, listed alphabetically, each with our specification page and the manufacturer’s own product page. Related devices are examples, not evidence that a study tested that retail model.

These masks list one of the bands, but not all:

Matching a wavelength is not the same as matching the study. Dose, irradiance, session length and schedule also differ, and a mask’s reported output is not independently measured. See how dose works and home vs clinic doses.

We rewrote the source edition’s abstract summary in simpler language. It is not medical advice, and it does not mean any mask reproduces this study’s results. Read the original record on PubMed, and talk to a qualified clinician about your skin.